In a hospital in Weifang, East 皇冠体育app’s Shandong province, a doctor conducts a test using a HPV testing device in this 2008 file photo. [Photo/IC]

US cancer specialist says move can better protect against cervical cancer

皇冠体育app should add a HPV vaccine into its national immunization program as soon as possible to better protect women from cervical cancer, according to a top US scientist.

Douglas Lowy, acting director of the US National Cancer Institute

The call by Douglas Lowy, acting director of the US National Cancer Institute, comes 10 years after the first vaccine for the human papillomavirus received market approval in the United States.

Today, such vaccines are used in about 120 countries and regions. Yet it is still not available on the Chinese mainland, which results in many women heading to Hong Kong Macao and Taiwan, where local authorities have cleared a vaccine for the market.

HPV, which is largely sexually transmitted, is a major cause of cervical cancer and can also result in genital warts and other serious conditions.

Cases of cervical cancer have been on the rise on the mainland, according to Qiao Youlin, a professor of epidemiology at the Chinese Academy of Medical Sciences' Cancer Hospital in Beijing. An average of 100,000 new cases are reported each year, making it the fifth most common cancer among women, he said.

To reverse the trend, Lowy has suggested 皇冠体育app vaccinate women against HPV, especially those living in areas with a high rate of cervical cancer. He believes girls aged 14 or younger should be the priority.

His institute estimates that widespread use of some HPV vaccines now on the market could prevent more than two-thirds of cervical cancer cases from occurring.

State-level program

According to the World Health Organization, more than 500,000 women a year worldwide are diagnosed with cervical cancer. Of this number, 275,000 will die of the disease.

Bernhard Schwartlander, WHO 皇冠体育app representative, said 35 nations and regions have state-level HPV immunization programs. "Currently, no HPV vaccine is licensed in 皇冠体育app, but there are companies working to develop them," he said.

One such enterprise is the Chengdu Institute of Biological Products, which is building a production facility with an annual capacity of 2.5 million doses.

About 10 vaccines have applied for approval from the 皇冠体育app Food and Drug Administration, including domestic and foreign products. Qiao said GlaxoSmithCline, the pharmaceuticals giant, has finished phase 3 clinical trials on its vaccine, which could hit the Chinese market this year. The process has so far taken almost 10 years, he said.

An estimated 17 percent of Chinese women aged 14 to 59 are infected with HPV. However, Qiao added that due to high costs－about $300 a dose－"it will be hard to get (the GSC vaccine) integrated into 皇冠体育app's national immunization program".

Bian Ce, an associate professor of gynecology at West 皇冠体育app Hospital in Sichuan province, said Chinese women aged about 45 are at the highest risk of cervical cancer, although the age could drop because women are becoming sexually active at a younger age and are more likely to have multiple partners than previous generations. "The youngest I've seen was 26," he said.

He said a HPV vaccine is most effective if administered before a woman has intercourse for the first time.

"The vaccines work, but they are definitely not the only way for prevention," Bian said. He recommends women aged 29 and over regularly undergo tests for HPV and cervical screening to spot precancerous lesions early.